비아그라 - 개요
비아그라 - 개요
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In experiments with wholesome volunteers of single doses as much as 800 mg, adverse reactions had been much like Individuals witnessed at decrease doses but incidence costs and severities were elevated.
VIAGRA may possibly impact how other medicines function, and various medicines could have an impact on the way VIAGRA performs, producing Negative effects. In particular convey to your Health care service provider if you take any of the following:
Sildenafil ordinarily shouldn't be taken over once each individual 24 hrs. If you have selected wellness conditions or are using certain drugs, your doctor might tell you to consider sildenafil less typically. You can take sildenafil with or without having food items. However, if you take sildenafil using a significant-Fats food, it will consider for a longer time to the medication to start to perform.
Within the celebration of an erection that persists more time than four hours, the client should seek out rapid healthcare support. If priapism is not really treated right away, penile tissue hurt and long-lasting lack of potency may outcome [see WARNINGS AND PRECAUTIONS].
This metabolite features a PDE selectivity profile similar to sildenafil and an in vitro potency for PDE5 roughly 50% of your mother or father drug. Plasma concentrations of this metabolite are roughly 40% of Those people found for sildenafil, so the metabolite accounts for about twenty% of sildenafil's pharmacologic results.
It is actually not possible to find out no matter whether these events are connected on to using PDE5 inhibitors, towards the individual's fundamental vascular hazard elements or anatomical defects, to a combination of these variables, or to other components [see WARNINGS AND Safety measures and Affected individual INFORMATION].
g., creatinine clearance < 30 mL/min), and concomitant usage of erythromycin or solid CYP3A4 inhibitors, plasma levels of sildenafil at 24 several hours put up dose have already been identified being three to eight instances greater than Those people witnessed in wholesome volunteers. Even though plasma amounts of sildenafil at 24 hours put up dose are much decreased than at peak 비아그라 concentration, it truly is unknown no matter if nitrates can be securely co-administered presently point [see CONTRAINDICATIONS].
Physicians ought to go over with individuals the contraindication of VIAGRA with normal and/or intermittent use of nitric oxide donors, such 정품비아그라 as natural and organic nitrates or natural and organic nitrites in any type [see CONTRAINDICATIONS].
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Doctors really should advise patients not to consider VIAGRA with other PDE5 inhibitors which includes REVATIO or other pulmonary arterial hypertension (PAH) solutions that contains sildenafil.
Medical professionals really should explore with sufferers the enhanced threat of NAION in individuals who have already professional NAION in a single eye. Physicians also needs to examine with individuals the increased possibility of NAION amongst the final populace in patients by using a “crowded�?optic disc, Even though proof is insufficient to assist screening of prospective end users of PDE5 inhibitor, including VIAGRA, for this unusual problem [see WARNINGS AND Safety measures and ADVERSE REACTIONS].
In several scenarios, clinical comply with-up details was restricted. It's impossible to find out regardless of whether these reported situations are relevant directly to the 비아그라 구입 usage of VIAGRA, towards the affected individual's underlying risk variables for hearing reduction, a mix of these elements, or to other things [see WARNINGS AND PRECAUTIONS and Client INFORMATION].
if you are taking sildenafil to treat erectile dysfunction, convey to your doctor When you have at any time been encouraged by a healthcare Skilled to prevent sexual exercise for professional medical good reasons or In case you have ever professional chest pain all through sexual action.